Multiple medications increase the risk of depression

Multiple medications increase the risk of depression

June 15, 2018 Source: Science and Technology Daily

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More than one-third of Americans know nothing about it

A new study in the United States says more than one-third of American adults may be using prescription drugs that cause depression or increase the risk of suicide, and they don't know anything about these risks. Researchers published a paper in the Journal of the American Medical Association warning that multiple medications increase the risk of depression and require high attention from health care providers and patients.

The study was conducted in collaboration with researchers at the University of Illinois at Chicago and Columbia University. They retrospectively analyzed the drug use patterns of more than 26,000 American adults between 2005 and 2014 and found more than 200 commonly used prescription drugs, including hormonal contraceptives, antihypertensive drugs, heart disease drugs, proton pump inhibitors, antacids, and analgesics. Drugs, etc., have potential side effects that lead to depression or suicidal tendencies. If you take these drugs at the same time, that is, multiple drugs, it will greatly increase the risk of depression and even suicide.

Researchers say that many people in daily life who take prescription drugs that are not associated with depression experience depression and are diagnosed with depression, which is likely to be the result of multiple medications. Research data show that about 15% of adults who take three or more of these drugs have depressive symptoms, compared with those who do not take any of them. Only 5%, 7% of people take one drug, and 9% of people who take both drugs.

Researchers point out that depression is one of the leading causes of disability and suicide in the United States, and the elimination or reduction of depression should be seen as an important public health issue. New research shows that even with commonly prescribed drugs, multiple drugs can cause depression. In recent years, the amount of drugs that may cause depression in the US commonly used prescription drugs is on the rise, but the users are ignorant of these risks. In response to this situation, the researchers suggest that on the one hand, it is necessary to strengthen the study of drug-drug interaction, and to regard depression as a potential drug risk into the research field; on the other hand, it is necessary to strictly control the drug regime and urge medical personnel to guide patients. Pay attention to the risk of multiple medications when taking medication. (Reporter Liu Haiying)

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