Release date: 2017-08-16
Transplant technology
Transplantation technology for the treatment of Parkinson's disease, such as stem cells, nerve cells, pig brain cells, etc., is the frontier of science and technology in Parkinson's field, especially in the past two years, China's ongoing research on stem cell treatment of Parkinson's disease is exciting.
In the case of Parkinson's drugs and devices, China has been following and imitating. Only stem cell technology, China is expected to accomplish its best and become a world-class company in a short time.
A unique case
Report of a case of neuronal cell transplantation for Parkinson's disease in the Proceedings of the National Academy of Sciences in Sweden at the University of Deron in 2016:
The case study lasted for 24 years and is the longest known follow-up case. What is even more rare is that the case was transplanted only on one side of the brain, just in contrast to the other side.
The patient developed symptoms of Parkinson's disease at the age of 50. The use of levodopa was very effective. At the age of 56, he had a "switching phenomenon" and at the age of 59 he underwent a nerve cell transplant.
Postoperative patients showed significant improvement in symptoms and levodopa was no longer needed for 3 years after transplantation. Brain imaging techniques have shown that dopamine function is normal in transplanted brain structures 10 years after surgery.
Some obvious reductions in efficacy began to appear 14 years after surgery, but still maintain a basic quality of life.
At 24 years after surgery, the case died of heart disease. The implanted dopaminergic neurons and the connections established between the cells still exist.
"Our findings show that transplanted nerve cells can survive in the patient's brain for many years, in parallel with their proper function," said research team member Professor Olle Lindvall. "This is also the first patient with Parkinson's disease who still shows such good dopaminergic neuron function after many years of cell transplantation. At the same time, we also found that when the disease spreads to other (other side) nerve regions in the brain, the symptoms begin. Gradually appeared."
The researchers continued to track a patient with Parkinson's disease who had undergone nerve cell transplantation for 24 consecutive years. The patient's postoperative symptoms were significantly improved and there was no need to use levodopa after three years of transplantation. Ten years after transplantation, brain imaging showed complete recovery of dopamine function in the brain of the patient's cell transplant side.
Through continuous tracking analysis of patients' brain function, the researchers have confirmed that after about a quarter of a century after cell transplantation, the implanted dopamine neurons and the connections established between the cells still exist.
"This research is unique," Professor Anders Bjrklund said. "There was no other cell transplant patient who had been closely followed for so long. Another unique feature of the case is that the patient only received a unilateral brain. Nerve cell transplantation, the brain hemisphere without cell transplantation on the other side just provides a comparative analysis for the researchers. Our research results have an irreplaceable value for future cell transplantation for Parkinson's disease."
Revelation and outlook
It can be seen from the report that although the transplantation technique can not solve Parkinson once and for all, it has great curative effect and can function for a long time.
Healing Parkinson, the future may change in philosophy. For patients with early-onset, long-term "functional cure" can be achieved, while patients with late-onset can bring Parkinson's disease into the coffin for a lifetime cure.
Technology has changed everything in the world.
"The 21st century is the century of biology." This annoying word is true!
Source: Payou Ecological Network
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