Testing the safety and effectiveness of new drugs is a very expensive process in the United States, and it also takes a lot of time. Now, this situation may change. Some scientists are designing computer silicon chips that work like human organs. Scientists believe that this method can make the process more economical and rapid.
The chip is smaller than the child's hand, and there are many living cells on each silicon chip, so that they can operate and react like human organs. The chip was developed for a project to test the safety of pharmaceutical compounds, which is called a "biological tissue chip."
The project was initiated by the National Center for Advanced Translational Science (NCATS). Danilo Tagle is the deputy director of NCATS. He said: "Scientists can design a three-dimensional computer chip that works like a human lung." And "in this case, the cells on the chip will replace the function of the alveoli and will be displayed on these bioengineered devices, allowing them to breathe and expand, absorbing air and fluid like normal lungs."
And some computer chips contain a very small human digestive system model. These chips mimic the function and function of the human stomach and small intestine, such as creeping when breaking down food.
The drug to be tested needs to be tested by a device called a microtube and then added to these tiny organs. Various tests using tissue microarrays can provide more detailed information than using animal or cell model tests.
Recently, the National Center for Advanced Translational Science has just announced a grant of $17 million for the development of a complete human organ system over the next three years.
Researchers at Columbia University are working on a project that combines models of the heart, liver, and circulatory system. Scientists hope to test the efficacy of some drugs for heart and liver diseases.
Researchers at Harvard University are developing a tissue chip based on heart and lung. The heart and lungs are part of the cardiopulmonary system and are vulnerable to some diseases. Since many new drugs may damage the heart, they failed during the test. Researchers at Harvard University hope to develop a cardiopulmonary system model that is immune to disease.
Researchers say they can safely test the effects of a drug on different organ systems. They can use tissue microarrays to observe the effects of a drug on an organ or its target organ.
Scientists want to make the drug development process easier, and hope that the chip will help them find the safest and most effective drugs before the start of human trials.
Edible Corn Starch,Custom Edible Starch,Liquid Starch Edible Powder,Starch Gluten Free
JILIN COFCO BIO-CHEM AND BIO-ENERGY MARKETING CO., LTD , https://www.cofco-biotech.com